The School of Instrumentation Science and Engineering (SISE) of Harbin Institute of Technology (HIT), founded in 1952, is the earliest Chinese subject dedicated to the issue of precision instruments. It is also one of the disciplines with an enormous scale and the most robust overall strength in China. Currently, it has three specialties for undergraduates: Precision Instruments, Measurement & Control Technology and Instruments, and IntelliSense Engineering.

Led by Professor Tan Jiubin, an academician of the Chinese Academy of Engineering (CAE), oriented in broad fields related to the manufacturing of high-grade, precision, and advanced equipment, largescale scientific projects, and precision medicine, SISE aims to the research and development of ultra-precision measurement methods and instrument technology, remote ultra-high-resolution laser measurement technology, label-free non-invasive microscopy methods and instrument technology, etc. It has developed a series of instruments based on new principles to solve critical measured problems in the abovementioned fields. In recent years, SISE has authorized more than 550 invention patents at home and abroad, established more than 30 international standards, national standards, and industry standards, published more than 1,200 high-level academic papers, and won more than 60 national and provincial major scientific and technological achievement awards represented by the first prize of National Technological Invention Award.

In Shanghai Ranking's Academic Ranking of World Universities, SISE ranked at the top from 2017 to 2019. It is an open and international school with long-term and substantive exchange and cooperation relationships with several international first-class laboratories, such as the University of Oxford, Physikalisch-Technische Bundesanstalt (PTB), and the National Physical Laboratory (NPL). With the help of CAE's international high-end instrument forum and the series of international symposiums on precision engineering measurement and instruments, SISE holds a large-scale international conference each year. Over 200 famous experts and scholars worldwide discuss and exchange ideas about new problems, technologies, and trends faced by the international front measurement and instrument field at the conference every year.

This series of conferences has become one of the top international conferences in measurement and instrumentation. In the direction of ultra-precision measurement methods and instrument technology, it proposed an error separation method to eliminate the theoretical errors of instruments and successfully developed a cylindrical measurement standard instrument based on new principles. After the testing and comparison with the measurement standard instruments of authoritative international laboratories, it is in the leading position of inaccuracy worldwide and makes such measurement values accurate and consistent. In the direction of remote ultra-high-resolution laser measurement technology, it proposed an active collaborative detection method with a spatial displacement resolution of 1 nm and power saving of more than 630 times, providing new technologies for future scientific experiments in space. In the direction of non-invasive microscopy methods and instrument technology, it presented a confocal optical and ultrasonic harmonic generation microscopy method, which enables the super-resolution and non-invasive imaging of 3D living cells and deep tissues, providing powerful tools for biomedical research and medical diagnostics. It solves a significant problem in the field of modern biomedical imaging. The scholars of SISE take the opportunity to quantize basic units in SI, which closely integrate digitalization, networking, intellectualization, and precision, utilizing the most advanced achievements in modern photonics, electronics, acoustics, materials, precision mechanics, dynamics, control, etc., with continuous efforts on new principle instruments invention and high-quality development of high-end equipment manufacturing, large-scale scientific engineering, and precision medicine.